Common mental disorders increase pre-eclampsia/ eclampsia risks in pregnancy

Main Article Content

Y Wibowo
M Hakimi
CR Marchira

Abstract

INTRODUCTION Pre-eclampsia is a multisystem complication that occurs after 20 weeks of pregnancy and can cause considerable maternal and fetal morbidity and mortality. Mental health is influenced by social support, and emotional distress during pregnancy may cause pre-ecclampsia/ecclampsia (PE/E). The objective of this study was to determine the association of social support and common mental disorders (CMD) with PE/E in pregnant women. METHODS This study was a matched case-control study. Cases were pregnant women who had been diagnosed with PE/E. Controls were those with normal pregnancies or not diagnosed as PE/E. Instruments social support questionnaire-6 (SSQ-6) was used to measure social support and self-reporting questionnaire 20 (SRQ-20) items for measuring CMD. Conditional logistic regression was used to estimate matched odds ratios (ORs) and 95% confidence intervals (95% CI). RESULTS Low social support was not directly associated with PE/E. Compared with women with high social support, those with low social support had a 26-fold increased risk of CMD (+) (OR=26.4, 95% CI: 10.67 to 77.20, p=0.001). Several variables significantly associated with PE/E were CMD (+) (OR=6.11, 95% CI: 2.99 to 14.07, p=0.001), low family income (OR=2.93, 95% CI: 1.56 to 5.82, p=0.001), history of chronic hypertension (+) (OR=7.67, 95% CI: 2.32 to 39.89, p=0.001), history of PE/E (+) (p=0.001), and history of hereditary PE/E (+) (OR=6, 95% CI: 1.34 to 55.20, p=0.013). CONCLUSION Low social support was not directly associated with PE/E but was associated with CMD. To prevent CMD in pregnant women, there is a need for social support from the family.

Article Details

How to Cite
Wibowo, Y., Hakimi, M., & Marchira, C. (2013). Common mental disorders increase pre-eclampsia/ eclampsia risks in pregnancy. Universa Medicina, 32(1), 60–68. https://doi.org/10.18051/UnivMed.2013.v32.60-68
Section
Review Article

References

Badan Perencanaan dan Pembangunan Nasional (Bappenas). Laporan pencapaian tujuan pembangunan milenium di Indonesia 2010. Jakarta: KPPN/Bappenas;2010.

Trogstad L, Magnus P, Stoltenberg C. Preeclampsia: risk factors and causal models. Best Pract Res Clin Obstet Gynaecol 2011;25:329–42.

Cunningham FG, Kenneth JL, Bloom SL, Hauth JC, Rouse DJ, et al. Williams Obstetrics. 23rd ed. New York: McGraw-Hill Companies Inc;2010.

Patel V, Kleinman A. Poverty and common mental disorders in developing countries. Bull World Health Organ 2003;81:609–15.

Santos IS, Matijasevich A, Tavares BF, da Cruz Lima AC, Riegel RE, Lopes BC. Comparing validity of Edinburgh scale and SRQ20 in screening for post-partum depression. Clin Pract Epidemiol Ment Health 2007;3:18.

Vianna P, Bauer ME, Dornfeld D, Chies JAB. Distress conditions during pregnancy may lead to pre-eclampsia by increasing cortisol levels and altering lymphocyte sensitivity to

glucocorticoids. Med Hypotheses 2011;77:188– 91.

Senturk V, Abas M, Berksun O, Stewart R. Social support and antenatal depression in extended and nuclear family environments in Turkey: a crosssectional survey. BMC Psychiatry 2011;11:48.

Shamsi U, Hatcher J, Shamsi A, Zuberi N, Qadri Z, Saleem S. A multicentre matched case control study of risk factors for Preeclampsia in healthy women in Pakistan. BMC Women’s Health

;10:14.

World Health Organozation. Maternal mental health and child health and development in low and middle income countries: report of the meeting held in Geneva, Switzerland. Geneva: World Health Organization;2008.

Faisal-Cury A, Menezes P, Araya R, Zugaib M. Common mental disorders during pregnancy: prevalence and associated factors among lowincome women in São Paulo, Brazil. Arch Womens Ment Health 2009;26;12:335–43.

Departemen Kesehatan R.I. Laporan riset kesehatan dasar (Riskesdas) nasional 2007. Jakarta: Depkes R.I.; 2008.

Mayer A, Erez O, Novack L, Bashiri A, Wiznitzer A, Mazor M. Chronic hypertension is an independent risk factor for preeclampsia and preterm delivery in women with rheumatologic

diseases: a population-based study. Eur J Obstet Gynecol Reprod Biol 2007;133:157–63.

Turagabeci AR, Nakamura K, Kizuki M, Takano T, et al. Family structure and health, how companionship acts as a buffer against ill health. Health Qual Life Outcomes 2007;5:61.

Dinas Kesehatan Propinsi Jawa Tengah. Profil Keehatan Propinsi Jawa Tengah Tahun 2008. Semarang: Din Kes Prop Jateng; 2009.

Elsenbruch S, Benson S, Rücke M, Rose M, Dudenhausen J, Pincus-Knackstedt MK, et al. Social support during pregnancy: effects on maternal depressive symptoms, smoking and

pregnancy outcome. Human Reprod 2007;22:869 – 77.

Sastroasmoro S, Ismael S. Dasar-dasar metodologi

penelitian klinis. 3rd ed. Jakarta: CV Sagung Seto; 2010.

Marchira CR. Hubungan dukungan sosial dengan insomnia pada lansia di poli geriatri RS DR Sardjito Yogyakarta [thesis]. Yogyakarta: Fakultas Kedokteran Universitas Gajah Mada;2004.

Idaiani S, Suhardi S, Kristanto AY. Analysis of mental emotional disorder symptoms in Indonesian people. JInMA 2011;59:10.

World Health Organization. A user’s guide to health reporting questionnaire (SRQ). Geneva: World Health Organization;1994.

Silva LM, Coolman M, Steegers EAP, Jaddoe VWV, Moll HA, Hofman A, et al. Low socioeconomic status is a risk factor for

preeclampsia: the generation R study. J Hypertens 2008;26:1200–8.

Rozikhan. Faktor-faktor risiko terjadinya preeklampsia berat di Rumah Sakit dr. H. Soewondo Kendal [thesis]. Semarang:

Universitas Diponegoro;2007.

Whitfield K, Weidner G, Clark R, Anderson N. Sociodemographic diversity and behavioral medicine. J Consult Clin Psychol 2002;70:463–81.

Yeo S, Steele N, Chang M, Leclaire S, Ronis D, Hayashi R. Effect of exercise on blood pressure in pregnant women with a high risk of gestational hypertensive disorders. J Reprod Med 2000;45: 293–8.

Siega-Riz A, Herrmann T, Savitz D, Thorp J. Frequency of eating during pregnancy and its effect on preterm delivery. Am J Epidemiol 2001; 153:647–52.

Wu CY, Prosser RA, Taylor JY. Association of depressive symptoms and social support on blood pressure among urban African American women and girls. J Am Acad Nurse Pract 2010;22: 694–704.

Taylor JY, Washington OGM, Artinian NT, Lichtenberg P. Relationship between depression and specific health indicators among hypertensive African American parents and

grandparents. Prog Cardiovascular Nurs 2008;23: 68–78.

Sibai B, Dekker G, Kupferminc M. Pre-eclampsia. The Lancet 2005;365:785–99.

Duckitt K, Harrington D. Risk factors for preeclampsia at antenatal booking: systematic review of controlled studies. BMJ 2005;330:565–70.

Chappell LC, Enye S, Seed P, Briley AL, Poston L, Shennan AH. Adverse perinatal outcomes and risk factors for preeclampsia in women with chronic hypertension: a prospective study. Hypertens 2008;51:1002–9.

Leff J, Vaughn C. Expressed emotion in families : its significance for mental illness. New York: The Guilford Press;1985.

Westdahl C, Milan S, Magriples U, Kershaw TS, Rising SS, Ickovics JR. Social support and social conflict as predictors of prenatal depression. Obstet Gynecol 2007;110:134.

Cohen S, Underwood LG, Gottlie RHE. Social support measurement and intervention a guide for health and social scientists. Oxford University Press; 2000. Available from: http://library.nu/ search:select. Accessed December 13, 2011.

Heinrichs M, Baumgartner T, Kirschbaum C, Ehlert U. Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress. Biol Psychiatry 2003;54: 1389–98.

Qiu C, Williams MA, Calderon-Margalit R, Cripe SM, Sorensen TK. Preeclampsia risk in relation to maternal mood and anxiety disorders diagnosed before or during early pregnancy. Am J Hypertens 2009;22:397–402.