Antagonism of vitamin C and vitamin E on action of quinolones

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Published: 2012-08-14
DOI: https://doi.org/10.18051/UnivMed.2012.v31.71-72

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Julius E. Surdjawidjaja
Department of Microbiology, Faculty of Medicine, Trisakti University

Abstract

The quinolone antibiotics are potent drugs for combating infections caused by various bacterial species with satisfactory results and relatively minimal adverse effects. Antioxidant dietary supplements, such as vitamin C (ascorbic acid) and vitamin E (a-tocopherol), are occasionally prescribed along with quinolone antibiotics during the course of treatment of an infection. Therefore it is important to understand the effects of these antioxidants on the antibacterial action of quinolone antibiotics.

Article Details

Issue

Vol. 31 No. 2 (2012)

Section

Review Article

The journal allows the authors to hold the copyright without restrictions and allow the authors to retain publishing rights without restrictions.

How to Cite

Antagonism of vitamin C and vitamin E on action of quinolones. (2012). Universa Medicina, 31(2), 71-72. https://doi.org/10.18051/UnivMed.2012.v31.71-72

References

Pfister K, Mazur D, Vormann J, Stahlmann R. Diminished ciprofloxacin-induced chondrocytotoxicity by supplementation with magnesium and vitamin E in immature rats. Antimicrob Agents Chemother 2007;51: 1022-7.

Gurbay A, Garrell C, Osman M, Richard MJ, Favier A, Hincal F. Cytotoxicity in ciprofloxacin-treated human fibroblast cells and protection by vitamin E. Hum Exper Toxicol 2002;12:635-41.

Gurbay A, Gonthier B, Barret L, Favier A, Hincal F. Cytotoxic effect of ciprofloxacin in primary culture of rat astrocytes and protection by vitamin E. Toxicol 2007;229:54-61.

Masadeh MM, Mhaidat NM, Alzoubi KH, Al-azzam SI, Shaweesh AI. Ciprofloxacin-induced antibacterial activity is reversed by vitamin E and vitamin C. Curr Microbiol 2012;64:457-62.

Hall MM, Finnoff JT, Smith J. Musculoskeletal complications of fluroquinolones: guidelines and precautions for usage in the athletic population. PMR 2011;3:132-42.