A 55 year old man with progressive neurologic deficits

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Published: 2009-08-29
Keywords:
Binswanger disease, irregular white matter abnormalities, multiple lacunar infarcts

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Sendjaja Muljadi
Department of Neurology, Medical Faculty, Trisakti University; Head of Neuroscience Centre, Medistra Hospital, Jakarta
Hardy Senjaya
Department of Anatomy, Mecical Faculty, Trisakti University, Jakarta

Abstract

At least 50 percent of the decline in functional abilities associated with the elderly is caused by neurological conditions, particularly vascular dementia, such as occurs in Binswanger disease. Binswanger disease is a rare condition, characterized by acute strokes with symptoms and signs compatible with lacunar infarction. The disease onset is commonly between 55 and 75 years. The majority of patients with Binswanger disease have chronic hypertension and other putative factors including diabetes mellitus, polycythemia, thrombocytosis, hyperlipidemia, hyperglobulinemia and pseudoxanthoma elasticum, increased fibrinogen levels and the antiphospholipid antibody syndrome. We report the case of a 55 year-old man, who suffered from involuntary movements of his right arm, slight hemiparesis on the right side, and also had dementia. He had a history of high blood pressure and laboratory tests showed that he had diabetes mellitus. The brain magnetic resonance imaging showed irregular white matter abnormalities with multiple lacunar infarcts in the basal ganglia and pons. The clinical picture is characterized by acute strokes, followed by involuntary movements and also dementia. Therefore we decided to diagnose it as Binswanger disease. After discharge from hospital, the patient has not returned for follow-up.

Article Details

Issue

Vol. 28 No. 2 (2009)

Section

Review Article

The journal allows the authors to hold the copyright without restrictions and allow the authors to retain publishing rights without restrictions.

How to Cite

A 55 year old man with progressive neurologic deficits. (2009). Universa Medicina, 28(2), 127-132. https://univmed.org/ejurnal/index.php/medicina/article/view/238

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